Buffers

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Topic Summary & Highlights
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Core Concept

A buffer is a solution that resists changes in pH when small amounts of acid ($H^+$) or base ($OH^−$) are added.

Key Components:

  1. Weak Acid and its Conjugate Base:

    • Example: Acetic acid ($CH_3COOH$) and acetate ($CH_3COO^−$).

  2. Weak Base and its Conjugate Acid:

    • Example: Ammonia ($NH_3$​) and ammonium ($NH_4^+$​).

Practice Tips

  • Buffers maintain a stable pH by neutralizing small amounts of added acid or base.

  • They consist of a weak acid and its conjugate base, or a weak base and its conjugate acid.

  • The Henderson-Hasselbalch equation is a vital tool for calculating buffer pH.

  • Buffer capacity increases with higher concentrations of buffering components and is optimal when [A−]≈[HA][\text{A}^-] \approx [\text{HA}][A−]≈[HA].

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How Do Buffers Work?

Buffers work through equilibrium reactions that neutralize added H+H^+H+ or OH−OH^-OH− ions:

  1. If Acid (H+H^+H+) is Added:

    • The conjugate base in the buffer reacts with the H+H^+H+, minimizing the increase in H+H^+H+ concentration.

    • Example: CH3COO−+H+→CH3COOHCH_3COO^- + H^+ \rightarrow CH_3COOHCH3​COO−+H+→CH3​COOH

  2. If Base (OH−OH^-OH−) is Added:

    • The weak acid in the buffer reacts with OH−OH^-OH−, minimizing the increase in OH−OH^-OH− concentration.

    • Example: CH3COOH+OH−→CH3COO−+H2OCH_3COOH + OH^- \rightarrow CH_3COO^- + H_2OCH3​COOH+OH−→CH3​COO−+H2​O

Types of Buffers

  1. Acidic Buffers:

    • Made from a weak acid and its conjugate base.

    • Example: Acetic acid (CH3COOHCH_3COOHCH3​COOH) and sodium acetate (CH3COONaCH_3COONaCH3​COONa).

    • pH < 7.

  2. Basic Buffers:

    • Made from a weak base and its conjugate acid.

    • Example: Ammonia (NH3NH_3NH3​) and ammonium chloride (NH4ClNH_4ClNH4​Cl).

    • pH > 7.

The Henderson-Hasselbalch Equation

The Henderson-Hasselbalch equation is used to calculate the pH of a buffer solution:

pH=pKa+log⁡([A−][HA])\text{pH} = \text{p}K_a + \log\left(\frac{[\text{A}^-]}{[\text{HA}]}\right)pH=pKa​+log([HA][A−]​)

Where:

  • [A−][\text{A}^-][A−]: Concentration of the conjugate base.

  • [HA][\text{HA}][HA]: Concentration of the weak acid.

  • pKa\text{p}K_apKa​: Negative logarithm of the acid dissociation constant (KaK_aKa​).

Key Points:

  • Buffers are most effective when [A−]≈[HA][\text{A}^-] \approx [\text{HA}][A−]≈[HA], or when pH≈pKa\text{pH} \approx \text{p}K_apH≈pKa​.

  • The effective buffering range is typically pKa±1\text{p}K_a \pm 1pKa​±1.

Buffer Capacity

  • Definition: The amount of acid or base a buffer can neutralize without a significant change in pH.

  • Factors Affecting Buffer Capacity:

    • Higher concentrations of the weak acid and conjugate base increase buffer capacity.

    • Optimal when [A−]≈[HA][\text{A}^-] \approx [\text{HA}][A−]≈[HA].

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